When you want to reach beyond the boundaries of conventional mass spectrometry, synapt g2 high definition mass spectrometry hdms provides a new dimension to your discovery. Find pricing on new and used waters synapt hdmss and other lab products. The hdi maldi solution provides a unique range of powerful multiplex targeted imsmsms and untargeted imsms e workflows from imagecentric method setup to data processing and image generation. The syanpt g2si measures the uptake of deuterium using the difference in protein mass that comes from the mass difference between exchanged deuterium 2. With highefficiency twave ion mobility, you can use an additional dimension of. Maldi synapt g2si hdms combines twave ims and quantof technology within a streamlined imaging workflow to deliver unparalleled selectivity, clarity and confidence. Synapt g2s hdms waters the mclean group laboratory. Synapt g2 and g1 both have similar instrument schematic except few differences in the ims cell. Synapt g1 high definition mass spectrometer duke gcb. Waters introduced the synapt g2 system at the 57th american society for. The system is complemented by mobility environment software to aid in the visualization and manipulation of highdefinition ms data. For more information on waters synapt g2s mass spectrometer, go to. Waters synapt g2 hdms shared instrumentation network.
Ability to upgrade your system with a high performance matrix assisted laser desorption ionization source for exact mass maldimsms analyses. Waters synapt g2si hdms the synapt g2si high definition mass spectrometer from waters is a hybrid quadrupole, ion mobility, orthogonal acceleration timeofflight oatof mass spectrometer that combines high resolution mass spectrometry with high efficiency ion mobilitybased measurements and separation ims. The maldi synapt g2si is powered by a solid state laser with a repetition rate of 2. The system combines exactmass, high resolution mass. Lastly, g2 could operate in higher traveling wave voltage and has different repeat pattern when. Waters maldi synapt hdms qtof lcmsms the waters maldi synapt hdms. During data acquisition with lock masscorrection, accurate mass measurements better than 5 ppm are obtained for elemental composition determinations of compounds that have a mz ratio of da. Synapt g2 hdms is a high resolution exact mass msms platform designed to get you to the right result, faster no matter how challenging your application is. Waters introduced the synapt g2 system at the 57th american society for mass spectrometry asms conference on mass spectrometry and allied topics in philadelphia, pa. Catalog number maldi synapt g2si hd this product is no longer available on biocompare. Maldi synapt g2si mass spectrometry from waters corporation. Learn about the benefits of ion mobility separations ims available with the synapt g2si mass spectrometer. Waters corporation introduces new synapt g2 with greater.
What is the latest version of masslynx software for the. With new driftscopetm mobility environment software v2. What is the latest version of masslynx software for the synapt. The tof mass range is 20 to 100,000 mz in resolution mode, and 20 to 32,000 mz in high resolution mode. Page 236 549 appiapci dualmode lockspray uplcmsms systems configuring maldi nanolockspray vacuum system 118 spare parts standby mode warning symbols starting synapt g2 working on source symbols workstation, connecting b21 caution electrical a11 handling a12 warning synapt g2 air filter, replacing 595. Features quantitative quadrupole timeofflight mass spectrometer quantoftm high resolution exact msms travelling wave ion mobility separation triwavetm cell, incl. Waters synapt hdms system enables the analysis of samples differentiated by size and shape, as well as mass, to deliver increased specificity and sample definition beyond that achievable by conventional mass spectrometers. Since its introduction in 2006, synapt hdms has set a new standard in highend ms instrumentation. General settings imaging was performed on two maldi synapt high definition mass spectrometer hdms g2is systems waters corporation, manchester, u. Synapt g2s hdms waters the mclean group laboratory for. The maldi synapt g2 hdms system is a hybrid, quadrupole, ion mobility, orthogonal acceleration, timeofflight oatof mass spectrometer controlled by masslynx software. To date there have been more than 150 research papers published to date based on triwave ion mobility synapt technology and more than 70 research papers on uplcmse. Maldi synapt g2si is a uniquely powerful and versatile ms platform. Our applications are mainly protein id and comparative proteomics and my feeling is that the hdms ims capabilities of the synapt g2s along with.
The waters synapt g2s high definition mass spectrometer hdms is used for discovery and targeted omicbased experiments. The waters synapt g2si high definition mass spectrometry provides complete characterization of complex mixtures and molecules with unique levels of ms performance, industry leading informatics and unparalleled platform versatility. The synapt g2 is an ion mobilitymass spectrometry imms instrument equipped with an electrosprayionization source. Synapt g2si hdms redefining resolution resolution in 3 dimensions. Quadrupole three modes can be used, no resolving dc voltage. Synapt high definition mass spectrometry is the combination of highefficiency ion mobility measurements and separations with highperformance tandem ms, enabling the differentiation.
High definition hybrid quadrupoletimeofflight mass spectrometer. For example, by combining maldi with ion mobility separations, waters high. In addition to the synapt g2 with full hdms capabilities, scientists have a choice of hdmsready products including the synapt g2 ms and maldi synapt g2 ms that can be upgraded on site to maximize the full potential of secondgeneration hdms functionality. Trap twave, ims twave, transfer twave stepwavetm ion optics video overview of the stepwavetm technology. April 2020english version windows 10 enterprise ltsb 1607. Gamechanging technology with high definition ms hdms defines new levels of. In the elevated energy plot, it is clearly seen that the fragments. To provide you with maximum utility and flexibility in your research laboratory, the synapt hdms system is compatible with a wide range of ionization sources. The waters synapt g2si high definition mass spectrometry provides complete characterization of complex mixtures and molecules with unique levels of ms. Synapt g2s ms with stepwave technology transforming your capacity for discovery, understanding, and success for mass spectrometry. Waters synapt g1 hdms high definition mass spectrometer. Waters synapt hdms designed for leading researchers working at the limits of conventional mass spectrometry capabilities who need to further characterize and define their samples, waters synapt hdms system offers unique, enabling functionality. With a unique upgrade pathway to meet your needs today and in the future, its designed to drive your research and business forward like no other ms system can, with. Waters introduces the synapt g2si to its mass spectrometer product line by.
It has an electrospray ionization esi interface, meaning that analytes need to be dissolved in mixture of aqueousorganic solution e. Protein facility office of biotechnology iowa state. Synapt provides the most complete characterization of complex mixtures and molecules with unique levels of ms performance, industry leading in. Synapt g2 is a qtof hybrid instrument, mainly used for small molecule mass analysis and hydrogendeuterium exchangemass spectrometry hdxms. Waters introduces the synapt g2si to its mass spectrometer product line. The signal from the detector is amplified, digitized, and sent to the masslynx software. Synapt g2 hdms waters the mclean group laboratory for. Waters synapt g2 mass spectrometerthe second generation. The system comes complete with hdms ion mobility, esi source, pumps, computer and masslynx software.
What is the latest version of masslynx software for the synapt g2 s. Maldi synapt g2s i high definition mass spectrometry from. Maldi synapt g2si high definition mass spectrometry. This waters synapt g2 hdms is sold refurbished with 3month warranty on parts. Access the highest levels of information content from your most analytically challenging samples, or utilize analytical tools to make scientific discoveries not possible by any other means. Waters synapt g2si high definition synapt g2si mass spectrometer, with a mass range up to 100,000 on mz scale in resolution mode, provides unique separation capability of highly complex samples in addition to hplc by its advanced twave ionmobility technology. Provides easy, rapid switch to api on the same platform. By combining stepwave plus quantof and triwave technologies, it provides a step change in ms performance. Uhplc acquity can be quoted alongside the mass spectrometer. Description synapt is a high resolution discovery maldi ms platform for imaging, biological research and chemical materials characterization, combining supreme performance with powerful workflows and unparalleled experimental versatility.
The instrument can be operated in the imms and in the ms only mode. For scientists this means performance in excess of 40,000 fwhm resolution, classleading sensitivity, a data acquisition rate of 20 spectrasecond, exact mass 1 ppm rms. Waters introduces new synapt g2 with greater power. Ability to upgrade your system with a high performance matrix assisted laser desorption ionization source for exact mass maldi msms analyses. A tradition of innovation in timeofflight mass spectrometry. The synapt g2si high definition mass spectrometer from waters is a hybridquadrupole, ionmobility, orthogonalacceleration timeofflight oatof mass spectrometer that combines high resolution mass spectrometry with highefficiency ion mobilitybased measurements and separation ims. Synapt g2si high definition mass spectrometry by waters corporation. Application note imaging using the ew umaldi source. Maldi synapt g2 hdms, waters, qimsoatof, ndyag 1 khz, to 40. Its the only way to combine multiple dimensions of separation for analysis of complex samples, from imaging to biological research to chemical materials characterization. The maldi synapt g2si ms system enables you to produce optimal results for imaging, chemical materials characterization, proteomics and pharmaceutical applications. B oth systems were tuned to conduct maldimsi experiments and fitted with a 2. Synapt g2, our secondgeneration platform, is the product of our very latest innovations. Operates in tof mode and hdms modezspray api sourcelockspray sourceesci esi and apci same so.
Synapt g2 mshdms series instruments installed with a maldi source accessory provide you with a nocompromise solution for the exact mass characterization of compounds using maldi ms, maldi msms, and maldi msimsms synapt g2 hdms series analyses. The system combines exactmass, high resolution mass spectrometry with highefficiency ionmobilitybased measurements and separation ims. Through highefficiency twave ion mobility you can get superior separation, enhance the peak capacity, specificity and sensitivity of your. The synapt g2 system is capable of outstanding qualitative and quantitative performance for both ms and the elevated data acquisition rates of synapt g2 hdms analysis. Denver, june 6, 2011 prnewswire waters corporation nyse.
Features quantitative quadrupole timeofflight mass spectrometer quantoftm high resolution exact msms travelling wave ion mobility separation twavetm video overview of the twavetm technology. The synapt hdms has dual resolution modes, vmode0 or wmode 17500. This hdms platform provides accurate mass measurements, multiple tandem mass spectrometry workflows, and ion mobility separation of complex mixtures. Schwarzgroup, equipment and experimental techniques. Waters introduces new synapt g2 with greater power, versatility. The synapt g2s system provides a unique platform to further your discovery efforts by expanding on the capabilities of conventional ms instrumentation. What is the latest version of masslynx software for the synapt g2. The waters synapt g2si system is utilized for protein applications such as proteinprotein interaction experiments. Waters synapt g2si high definition mass spectrometry center. Waters introduces synapt g2s mass spectrometer, combining. After ion generation by electrospray, parent ions can be.
Sometimes chromatography and mass resolution are not enough. In addition, g2 could go up to higher pressure than g1. Which qtof is best abs triple tof5600 or waters g2s. Maldi synapt g2si high definition mass spectrometry from. Triwave technology triwave technology is the enabling technology behind the synapt g2 hdms system. Designed for leading researchers working at the limits of conventional mass spectrometery capabilities who need to further characterize and define their samples, waters synapt tm hdms tm system offers unique, enabling functionality waters synapt hdms tm system enables analysis of samples differentiated by size and shape. Waters synapt g1 hdms qtof mass spectrometer with software.
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